Product ID: HVA113
Antibodies
| OVERVIEW | |
|---|---|
| This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008] | |
| Product Details | |
| Application | 10k-ChIP; IHC; WB |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Clonality | Monoclonal |
| Concentration | 1.0 mg/ml |
| Conjugation | Unconjugated |
| Host Species | Mouse |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22 - 319 of human CD68 (NP_001242), produced in SF9 cell. |
| Isotype | IgG1 |
| NCBI Accession Number | NP_001242 |
| Protein Families | Druggable Genome, Transmembrane |
| Purification | Affinity purification |
| Recommended Dilution | WB 1:2000; IHC 1:100~200 |
| Shipping | Shipping with blue ice. |
| Synonyms | GP110; LAMP4; SCARD1 |
| Target Species | Human |
| UniProt ID | P34810 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
