Immunohistochemistry (IHC), which utilizes monoclonal and polyclonal antibodies to detect specific antigens in situ, is a very powerful tool for imaging discrete components in tissues.
The science of IHC is evolving, as evidenced by the development of increasingly sophisticated automated staining platforms, production of specific antibodies against a wide range of species, and the availability of a range of novel biomarkers.
IHC studies with optimized staining protocols for specific target expression/profiling in human and animal tissues can be used for a variety of reasons, such as proliferation/apoptosis studies, immuno-oncology, tumor profiling and tissue cross reactivity.
Creative Bioarray has highly trained and knowledgeable staff that work with investigators to provide the best approach to meet the goals of the project. We have hundreds of established antibody protocols on various species, and we are constantly optimizing additional antibodies.
Creative Bioarray has invested in innovation through a fully equipped histopathology laboratory. We offer:
4-1BB | 4HNE | 5T4 | ACE2 |
Actin | Adipophilin | AE1/AE3 (pancytokeratin) | Alpha-Fetoprotein |
Alpha-SMA | Bcl-2 | Bcl-6 | Beta-amyloid |
Beta-Catenin | Beta-galactosidase | Beta-Tubulin | BrdU |
Caspase-3 | CD10 | CD11b | CD138 |
CD15 | CD18 | CD1a | CD20 |
CD23 | CD25 | CD274 (PD-L1) | CD3 |
CD30 | CD31 | CD34 | CD4 |
CD40 | CD43 | CD44 | CD45lca |
CD45R (B220) | CD5 | CD56 | CD57 |
CD68 | CD7 | CD79a | CD8 |
CDX2 | Chromogranin A | CK18 | C-kit (CD117) |
Claudin-3 | COX2 | Cyclin D1 | Cytokeratin |
DCX | Desmin | E-Cadherin | ER |
F4/80 | Factor VIII | FIPV | Foxp3 |
Gastrin | GATA-3 | GFAP | GFP |
Glucagon | Granzyme B | HER2 | HMGB1 |
IBA1 | Insulin | Ki-67 | Lambda light chains |
Laminin | LY6G | MAC 387 | Mac-2 |
Melan A | MUC 5AC | MUC 5B | MUM-1 |
Myeloperoxidase (MPO) | Myoglobin | Neuron specific enolase | Neuronal nuclei |
Nitrotyrosine | Olig2 | OX-40 | p53 |
p63 | Pancytokeratin | Papillomavirus | Parathyroid hormone |
PCNA | PDCD1 (PD-1) | PDX-1 | Phospho-Akt |
Phospho-histone H2A.X | PNA | PNL-2 | S100 |
Somatostatin | SOX-9 | STAT-6 | Synaptophysin |
TdT | TER-119 | TGF-β | Thyroglobulin |
Thyroid transcription factor (TTF-1) | TIM-3 | TNF-α | TRP-1 |
TRP-2 | Tyrosine hydroxylase | VEGF | VEGF |
Von Willebrand Factor |
Immunofluorescence and antibody validation for IHC not listed are available upon request. Contact us to discuss your needs.
We have extensive experience testing antibodies in both human and animal tissues. Contact us to arrange a consultation.