Product ID: HVA126
Antibodies
| OVERVIEW | |
|---|---|
| This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011] | |
| Product Details | |
| Application | IF; IHC |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Clonality | Monoclonal |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Conjugation | Unconjugated |
| Host Species | Mouse |
| Immunogen | Recombinant human AMACR (NP_055139) full - length protein, produced in HEK293T cell. |
| Isotype | IgG1 |
| NCBI Accession Number | NP_055139 |
| Predicted Protein Size | 42.2 kDa |
| Protein Families | Druggable Genome |
| Purification | Affinity purification |
| Recommended Dilution | IHC 1:100 |
| Shipping | Shipping with blue ice. |
| Synonyms | AMACRD; CBAS4; RACE; RM |
| Target Species | Human |
| UniProt ID | Q9UHK6 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
