Product ID: HVA57
Antibodies
| OVERVIEW | |
|---|---|
| The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015] | |
| Product Details | |
| Application | IHC |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Clonality | Monoclonal |
| Concentration | 1.00mg/ml |
| Conjugation | Unconjugated |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human BCL6 (NP_001697). The exact sequence is proprietary. |
| Isotype | IgG |
| NCBI Accession Number | NP_001697 |
| Predicted Protein Size | 78.7 kDa |
| Protein Families | Druggable Genome, Transcription Factors |
| Purification | Affinity purification |
| Recommended Dilution | IHC 1:1200 |
| Shipping | Shipping with blue ice. |
| Synonyms | BCL5; BCL6A; LAZ3; ZBTB27; ZNF51 |
| Target Species | Human |
| UniProt ID | P41182 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
