Product ID: HVA58
Antibodies
OVERVIEW | |
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This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008] | |
Product Details | |
Application | IHC; WB |
Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Clonality | Monoclonal |
Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
Conjugation | Unconjugated |
Host Species | Mouse |
Immunogen | Recombinant human BID (NP_001187) full - length protein, produced in HEK293T cell. |
Isotype | IgG2b |
NCBI Accession Number | NP_001187 |
Protein Families | Druggable Genome |
Purification | Affinity purification |
Recommended Dilution | WB 1:2000; IHC 1:200 |
Shipping | Shipping with blue ice. |
Synonyms | FP497 |
Target Species | Human |
UniProt ID | P55957 |
Storage | Stored at -20°C for 1 year |
LIMITATIONS | |
All products are for research use only. |