Product ID: HVA123
Antibodies
| OVERVIEW | |
|---|---|
| Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] | |
| Product Details | |
| Application | IF; IHC; WB |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Clonality | Monoclonal |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Conjugation | Unconjugated |
| Host Species | Mouse |
| Immunogen | Recombinant human CA12 (NP_001209) full - length protein, produced in HEK293T cell. |
| Isotype | IgG2a |
| NCBI Accession Number | NP_001209 |
| Predicted Protein Size | 36.8 kDa |
| Protein Families | Druggable Genome, Transmembrane |
| Purification | Affinity purification |
| Recommended Dilution | IHC 1:100~200 |
| Shipping | Shipping with blue ice. |
| Synonyms | CAXII; HsT18816 |
| Target Species | Human |
| UniProt ID | O43570 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
