Product ID: HVA27
Antibodies
| OVERVIEW | |
|---|---|
| The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] | |
| Product Details | |
| Application | IF; IHC; LMNX; WB |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
| Clonality | Monoclonal |
| Concentration | 0.5 mg/ml |
| Conjugation | HRP |
| Host Species | Mouse |
| Immunogen | Recombinant human CD163 (NP_004235) full-length protein, produced in HEK293T cell. |
| Isotype | IgG2a |
| NCBI Accession Number | NP_004235 |
| Predicted Protein Size | 125.3 kDa |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Purification | Affinity purification |
| Recommended Dilution | WB 1:200~4000; IHC 1:150; IF 1:100 |
| Shipping | Shipping with blue ice. |
| Synonyms | M130; MM130; SCARI1 |
| Target Species | Human |
| UniProt ID | Q86VB7 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
