Product ID: HVA12
Antibodies
| OVERVIEW | |
|---|---|
| The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008] | |
| Product Details | |
| Application | IF; WB |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Host Species | Mouse |
| Immunogen | Recombinant human CD3E (NP_000724) full-length protein, produced in HEK293T cell. |
| Isotype | IgG2b |
| NCBI Accession Number | NP_000724 |
| Predicted Protein Size | 20.7 kDa |
| Protein Families | Druggable Genome, Transmembrane |
| Purification | Affinity purification |
| Recommended Dilution | WB 1:500; IF 1:100 |
| Shipping | Shipping with blue ice. |
| Synonyms | IMD18; T3E; TCRE |
| Target Species | Human |
| UniProt ID | P07766 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
