Product ID: HVA104
Antibodies
| OVERVIEW | |
|---|---|
| The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010] | |
| Product Details | |
| Application | 10k-ChIP; IF; IHC; WB |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Clonality | Monoclonal |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Conjugation | Unconjugated |
| Host Species | Mouse |
| Immunogen | Recombinant human EGFR (NP_958440) full - length protein, produced in HEK293T cell. |
| Isotype | IgG1 |
| NCBI Accession Number | NP_958440 |
| Predicted Protein Size | 42.4 kDa |
| Protein Families | Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Secreted Protein, Stem cell relevant signaling - JAK/STAT signaling pathway, Transmembrane |
| Purification | Affinity purification |
| Recommended Dilution | WB 1:500; IHC 1:100 |
| Shipping | Shipping with blue ice. |
| Synonyms | ERBB; ERBB1; ERRP; HER1; mENA; NISBD2; PIG61 |
| Target Species | Human; Monkey; Mouse; Rat |
| UniProt ID | P00533 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
