| The FFPE Tissue Protein Extraction Kit uses a proprietary decrosslinking technology to extract proteins from formalin-fixed paraffin-embedded (FFPE) specimens. It combines selective chelating agents and recombinant proteases to reverse fixation-induced crosslinks, recovering full-length proteins with preserved epitopes and post-translational modifications.
The kit replaces harsh alkaline hydrolysis or prolonged heating with pH-modulated enzymatic digestion under non-denaturing conditions, maintaining protein functionality. The workflow yields extracts suitable for high-sensitivity analyses like MS/MS, RPPA, and multiplex immunoassays. |
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