Product ID: HVA91
Antibodies
| OVERVIEW | |
|---|---|
| This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010] | |
| Product Details | |
| Application | 10k-ChIP; IF; IHC |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Clonality | Monoclonal |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Conjugation | Unconjugated |
| Host Species | Mouse |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 40 - 315 of human GBA (NP_000148), produced in E. coli. |
| Isotype | IgG2a |
| NCBI Accession Number | NP_000148 |
| Predicted Protein Size | 55.5 kDa |
| Protein Families | Druggable Genome |
| Purification | Affinity purification |
| Recommended Dilution | IHC 1:100~200 |
| Shipping | Shipping with blue ice. |
| Synonyms | GBA1; GCB; GLUC |
| Target Species | Human; Mouse; Rat |
| UniProt ID | P04062 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
