Product ID: HVA61
Antibodies
| OVERVIEW | |
|---|---|
| The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] | |
| Product Details | |
| Application | IHC |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Clonality | Monoclonal |
| Concentration | 1.00mg/ml |
| Conjugation | Unconjugated |
| Host Species | Rabbit |
| Immunogen | Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human GS (Glul) (NP_001028228). The exact sequence is proprietary. |
| Isotype | IgG |
| NCBI Accession Number | NP_001028228 |
| Predicted Protein Size | 42.1 kDa |
| Purification | Affinity purification |
| Recommended Dilution | IHC 1:600 |
| Shipping | Shipping with blue ice. |
| Synonyms | GLNS; GS; PIG43; PIG59 |
| Target Species | Human |
| UniProt ID | P15104 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
