Product ID: HVA85
Antibodies
| OVERVIEW | |
|---|---|
| The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq, Jul 2008] | |
| Product Details | |
| Application | IF; IHC; WB |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Clonality | Monoclonal |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Conjugation | Unconjugated |
| Host Species | Mouse |
| Immunogen | Recombinant human L1CAM (NP_000416) full - length protein, produced in HEK293T cell. |
| Isotype | IgG1 |
| NCBI Accession Number | NP_000416 |
| Predicted Protein Size | 137.8 kDa |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Purification | Affinity purification |
| Recommended Dilution | IHC 1:100 |
| Shipping | Shipping with blue ice. |
| Synonyms | CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1 |
| Target Species | Human; Mouse; Rat |
| UniProt ID | P32004 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
