Product ID: HVA79
Antibodies
| OVERVIEW | |
|---|---|
| This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. [provided by RefSeq, Nov 2009] | |
| Product Details | |
| Application | IF; IHC; WB |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Clonality | Monoclonal |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Conjugation | Unconjugated |
| Host Species | Mouse |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 299 - 527 of human MLH1 (NP_000240), produced in E. coli. |
| Isotype | IgG1 |
| NCBI Accession Number | NP_000236 |
| Predicted Protein Size | 84.4 kDa |
| Protein Families | Druggable Genome |
| Purification | Affinity purification |
| Recommended Dilution | IHC 1:200 |
| Shipping | Shipping with blue ice. |
| Synonyms | COCA2; FCC2; hMLH1; HNPCC; HNPCC2; MMRCS1 |
| Target Species | Human; Mouse; Rat |
| UniProt ID | P08581 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
