Product ID: HVA78
Antibodies
| OVERVIEW | |
|---|---|
| Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008] | |
| Product Details | |
| Application | 10k-ChIP; IHC; WB |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Clonality | Monoclonal |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Conjugation | Unconjugated |
| Host Species | Mouse |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 95 - 267 of human MMP7 (NP_002414), produced in E. coli. |
| Isotype | IgG1 |
| NCBI Accession Number | NP_002403 |
| Predicted Protein Size | 19.1 kDa |
| Protein Families | Druggable Genome, Protease |
| Purification | Affinity purification |
| Recommended Dilution | IHC 1:100~200 |
| Shipping | Shipping with blue ice. |
| Synonyms | MMP-7; MPSL1; PUMP-1 |
| Target Species | Human |
| UniProt ID | P16455 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
