Product ID: HVA72
Antibodies
| OVERVIEW | |
|---|---|
| This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] | |
| Product Details | |
| Application | IHC |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Clonality | Monoclonal |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Conjugation | Unconjugated |
| Host Species | Mouse |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1 - 304 of human MSH2 (NP_000242), produced in E. coli. |
| Isotype | IgG2b |
| NCBI Accession Number | NP_000242 |
| Predicted Protein Size | 104.6 kDa |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Purification | Affinity purification |
| Recommended Dilution | IHC 1:2400 |
| Shipping | Shipping with blue ice. |
| Synonyms | COCA1; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2; MMRCS2 |
| Target Species | Human; Mouse; Rat |
| UniProt ID | P43246 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
