Product ID: HVA52
Antibodies
| OVERVIEW | |
|---|---|
| This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar | |
| Product Details | |
| Application | 10k-ChIP; IF; IHC |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Clonality | Monoclonal |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Conjugation | Unconjugated |
| Host Species | Mouse |
| Immunogen | Recombinant human PBX1(NP_002576) full-length protein, produced in HEK293T cell. |
| Isotype | IgG1 |
| NCBI Accession Number | NP_002576 |
| Predicted Protein Size | 46.4 kDa |
| Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
| Purification | Affinity purification |
| Recommended Dilution | IHC 1:100~200 |
| Shipping | Shipping with blue ice. |
| Synonyms | DKFZp686B09108; MGC126627 |
| Target Species | Human; Mouse; Rat |
| UniProt ID | P40424 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
