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PCNA Mouse Monoclonal Antibody

Product ID: HVA53

Antibodies

OVERVIEW
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
Product Details
Application IHC
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clonality Monoclonal
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Conjugation Unconjugated
Host Species Mouse
Immunogen Recombinant human PCNA (NP_002583) full-length protein, produced in E. coli.
Isotype IgG1
NCBI Accession Number NP_002583
Predicted Protein Size 28.6 kDa
Protein Families Druggable Genome, Stem cell - Pluripotency
Purification Affinity purification
Recommended Dilution IHC 1:4000
Shipping Shipping with blue ice.
Synonyms ATLD2
Target Species Human; Mouse; Rat
UniProt ID P12004
Storage Stored at -20°C for 1 year
LIMITATIONS
All products are for research use only.


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