Product ID: HVA48
Antibodies
| OVERVIEW | |
|---|---|
| This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq, Jul 2008] | |
| Product Details | |
| Application | IF; IHC; WB |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Clonality | Monoclonal |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Conjugation | Unconjugated |
| Host Species | Mouse |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 541-792 of human RRM1 (NP_001024) produced in E.coli. |
| Isotype | IgG1 |
| NCBI Accession Number | NP_001024 |
| Predicted Protein Size | 89.9 kDa |
| Protein Families | Druggable Genome |
| Purification | Affinity purification |
| Recommended Dilution | IHC 1:200 |
| Shipping | Shipping with blue ice. |
| Synonyms | R1; RIR1; RR1 |
| Target Species | Human; Mouse; Rat |
| UniProt ID | P23921 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
