Product ID: HVA39
Antibodies
| OVERVIEW | |
|---|---|
| This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb | |
| Product Details | |
| Application | 10k-ChIP; IF; IHC |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Clonality | Monoclonal |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Conjugation | Unconjugated |
| Host Species | Mouse |
| Immunogen | Recombinant human TNFRSF18 (NP_004186) protein fragment corresponding to amino acids 26-162, produced in E.coli. |
| Isotype | IgG2b |
| NCBI Accession Number | NP_004186 |
| Predicted Protein Size | 23.5 kDa |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Purification | Affinity purification |
| Recommended Dilution | IHC 1:100~200 |
| Shipping | Shipping with blue ice. |
| Synonyms | AITR; CD357; GITR; GITR-D |
| Target Species | Human |
| UniProt ID | Q9Y5U5 |
| Storage | Stored at -20°C for 1 year |
| LIMITATIONS | |
| All products are for research use only. | |
